Correlation between standard renogram and histology for the etiological diagnosis of Graft dysfunction in renal transplant patients in the Hospital San Vicente Foundation in Medellín, Colombia, from January 2009 to December 2013: a series of cases
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Keywords

Rejection
graft biopsy
scintigraphy
transplant.

How to Cite

1.
Baquero Rodriguez R, Gutierrez Tamayo AM, Londoño Blair JL, Cornejo Ochoa JW, Arias Restrepo LF, Vanegas Ruiz JJ, Pereira Gomez MDP. Correlation between standard renogram and histology for the etiological diagnosis of Graft dysfunction in renal transplant patients in the Hospital San Vicente Foundation in Medellín, Colombia, from January 2009 to December 2013: a series of cases. Rev. Colomb. Nefrol. [Internet]. 2016 Nov. 18 [cited 2024 Mar. 28];3(2):80-8. Available from: https://revistanefrologia.org/index.php/rcn/article/view/216

Abstract

Objective: Find the correlation between renal biopsy and renogram for evaluation of complications of renal transplantation.

Methods: Correlation study, descriptive and retrospective records of patients who attended the kidney transplant service at the University Hospital Foundation San Vicente diagnosed with graft dysfunction in the period between January 2009 and December 2013.

Criteria were reviewed inclusion in the study: Renal biopsy and standard MAG3 or DTPA renogram also demographic variables.

Results: 33 medical records, only 18 eligible patients with the inclusion criteria were reviewed. We documented rejection in 7 patients with renal biopsies and 3 scans. In 11 patients without rejection was found by biopsy, scintigraphy ruled it in 6 of them. This translates into 42 % sensitivity (CI 0-86) and 45 % specificity (20-88), with a PPV of 33 % (CI 0-77) and NPV of 44% (CI 24-95).

Conclusion: Our results differ from previous studies because renogram performance in our sample was poor for both rejection to acute tubular necrosis. Several independent factors could be related to our results.

https://doi.org/10.22265/acnef.3.2.216
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