Keywords
Chronic Kidney Disease
Diabetic Kidney Disease
Diabetic Nephropathy
Albuminuria
Creatinine
Clinical Guidelines
How to Cite
Abstract
Context: Diabetes remains one of the most extensively studied diseases, yet microvascular complications, such as kidney damage, persist. In the past decade, new therapies—including sodium-glucose cotransporter-2 inhibitors (SGLT2i), glucagon-like peptide-1 receptor agonists (GLP-1 RAs), and nonsteroidal mineralocorticoid receptor antagonists (nsMRAs)—have demonstrated renal and cardiovascular benefits, supporting safer clinical recommendations.
Objective: To update the 2021 Clinical Practice Guideline (CPG) for diabetic kidney disease (DKD), emphasizing the role of multidisciplinary and holistic care.
Methodology: The methodology from 2021 was replicated according to standards from the Colombian Ministry of Health and IETS. Evidence from January 2021 to December 2023 was gathered and assessed with AGREE II. Recommendations were reviewed to ensure current relevance within the Colombian context. Patient perspectives were incorporated through surveys from seven individuals with DKD.
Results: Seven key clinical questions were addressed using the ADA, KDIGO, EASC 2023, and Paraguayan DKD guidelines. The recommendations highlight the benefits of these new therapies and the importance of integrated care. Qualitative analysis revealed patients’ concerns regarding DKD, treatments, and access to care.
Conclusions: This guideline enhances DKD interventions, emphasizing the need to include patient perspectives and improve implementation to support effective DKD management.
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