Colombian consensus of experts on evidence -based recommendations for diagnosis, treatment and follow-up of fabry’s disease with renal involvement
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Fabry Disease
Enzyme Replacement Therapy
Consensus Conference

How to Cite

Barros Camargo LR, Jiménez SJ, Roncallo A, López F, Conde JC, Martínez T, Lopera Vargas JM, Garzón M, Chacón Acevedo KR, Politei J, Jaurretche S, Olivares O, López JG, Ferrari GM, Ibarra J. Colombian consensus of experts on evidence -based recommendations for diagnosis, treatment and follow-up of fabry’s disease with renal involvement. Rev. Colomb. Nefrol. [Internet]. 2022 Feb. 24 [cited 2022 May 18];9(1):e591. Available from:


Background: Fabry disease behaves like a chronic condition, with multisystem involvement and high health care costs.

Objective: To generate evidence-based recommendations for the diagnosis, treatment and follow-up of the Anderson-Fabry disease with renal commitment, through an expert consensus.

Methodology: Based on the search of evidence in PubMed, Embase and Google Scholar between 2010 and August, 2020, recommendations on the definition, diagnosis and treatment of Fabry Disease in adult population were formulated after consulting with an expert panel through the modified Delphi consensus methodology. The quality of the documents was assessed by methodological team applying tools according to the type of document included.

Results: 53 recommendations for the definition, diagnosis and treatment were formulated. A panel of five national and international clinical experts external to the developer group participated in the pre-consensus consultation and 50 recommendations were agreed upon for their inclusion. For 3 recommendations, a formal consensus session which took place in one round was required, and 3 new recommendations were incorporated.

Conclusions: The recommendations based on evidence and clinical expertise will allow us to guide the diagnosis and treatment of patients with Fabry disease with renal involvement or suspicion thereof in a standardized manner at national and regional levels.
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