Adherence to treatment of patients with arterial hypertension in a University Hospital in Colombia
PDF (Español)
XML (Español)

Keywords

hypertension
medication
nonadherence
lifestyle
chronic disease
eligibility
insurance

How to Cite

1.
Barón Barón JO, Fernández-Ávila DG, Cárdenas Guio S, Duitama González EL, Calderón Cerquera TV, Romero Trillos LA, Mesa Aponte JD, Castillo Correa JP, Chinchilla Pérez DS, Vargas Rodríguez LJ. Adherence to treatment of patients with arterial hypertension in a University Hospital in Colombia. Rev. Colomb. Nefrol. [Internet]. 2025 May 19 [cited 2025 Sep. 10];12(1). Available from: https://revistanefrologia.org/index.php/rcn/article/view/806

Abstract

Background: Arterial hypertension is one of the most prevalent who did not modifiable risk factors for cardiovascular disease. For an optimal control of this disease, it is important that patients have a good adherence to treatment, however, non compliance with treatment is still a frequent problem.

Purpose: To characterize sociodemographically adherence to pharmacological treatment and identify the factors associated with therapeutic non-compliance in patients with arterial hypertension attending in a university hospital of Colombia.

Methodology: This was an observational, descriptive, cross-sectional study. The entire population with a diagnosis of arterial hypertension who received care between April 1 and May 31, 2021 was included. The Morisky scale (MMAS-8) was used to assess adherence to pharmacological treatment.

Results: 400 patients were included, of wich 56% were men. 14% of the patients were adherent to pharmacological treatment versus 86% who did not. The most frequently cause of non-adherence was the failure of the health insurers to supply medicines (49%).

Conclusion: Non- adherence to pharmacological treatment remains a major barrier to achieving adequate control of chronic diseases.

https://doi.org/10.22265/acnef.12.1.806
PDF (Español)
XML (Español)

References

Berenguer Guarnaluses LJ. Algunas consideraciones sobre la hipertensión arterial. Medisan. 2016;20(11):2434.

Tagle R. Diagnóstico de la hipertensión arterial. Revista Médica Clínica Condes. 2018;29(1):12-20. https://doi.org/10.1016/j.rmclc.2017.12.005

Wyss F, Valdez O, Camafort M, Coca A. Abordaje terapéutico integral de la hipertensión arterial. Recomendaciones para Centroamérica y el Caribe. Hipertens Riesgo Vasc. 2023;40(1):40-7. https://doi.org/10.1016/j.hipert.2022.05.004.

Lear SA, Hu W, Rangarajan S, Gasevic D, Leong D, Iqbal R, et al. The effect of physical activity on mortality and cardiovascular disease in 130?000 people from 17 high-income, middle-income, and low-income countries: the PURE study. Lancet. 2017;390(10113):2643-54. http://dx.doi.org/10.1016/S0140-6736(17)31634-3

Unger T, Borghi C, Charchar F, Khan NA, Poulter NR, Prabhakaran D, et al. 2020 International Society of Hypertension. Global Hypertension Practice Guidelines. Hypertension. 2020;75(6):1334-57. https://doi.org/10.1161/hypertensionaha.120.15026

Guerra MG. Hypertensive Patient Adherence To Treatment: the Use of Therapeutic Communication Associated With Technology Educational in Health Promotion. 2017;(Dl):23-5. https://app.dimensions.ai/details/grant/grant.4477194

García-Peña ÁA, Ospina D, Rico J, Fernández-Ávila DG, Muñoz-Velandia Ó, Suárez-Obando F. Prevalence of arterial hypertension in Colombia according to data from the Comprehensive Social Protection Information System (SISPRO). Rev Colomb Cardiol. 2022;29(1):29-35. https://doi.org/10.24875/rccar.m22000114

Zurique-Sánchez MS, Zurique-Sánchez CP, Camacho-López PA, Sánchez-Sanabria MS, Hernández-Hernández SC. Prevalencia de hipertensión arterial en Colombia: revisión sistemática y metaanálisis. Acta Méd Colomb. 2019;44(4). https://doi.org/10.36104/amc.2019.1293

Zyoud SH, Al-Jabi SW, Sweileh WM, Wildali AH, Saleem HM, Aysa HA, et al. Health-related quality of life associated with treatment adherence in patients with hypertension: a cross-sectional study. Int J Cardiol. 2013;168(3):2981-3. http://dx.doi.org/10.1016/j.ijcard.2013.04.105

Holguín Palacios LE, Correa D, Arrivillaga M, Cáceres D, Varela M. Adherencia al tratamiento de hipertensión arterial: efectividad de un programa de intervención biopsicosocial. Univ Psychol. 2006;5(3):511-48.

Valencia-Monsalvez F, Mendoza-Parra S, Luengo-Machuca L. Evaluation of Morisky medication adherence scale (MMAS-8) in older adults of a primary health care center in Chile. Rev Peru Med Exp Salud Pública. 2017;34(2):245-9. https://doi.org/10.17843/rpmesp.2017.342.2206

Suárez-Argüello J, Blanco-Castillo L, Perea-Rangel JA, Villarreal-Ríos E, Vargas-Daza ER, Galicia-Rodríguez L, et al. Disease belief, medication belief and adherence to treatment in patients with high blood pressure. Arch Cardiol Mex. 2022;92(3):327-33. https://doi.org/10.24875/acm.21000026

Delucchi A, Marín M, Páez O, Bendersky M, Rodríguez P. Principales conclusiones del Consenso Argentino de Hipertensión Arterial. Hipertens Riesgo Vasc. 2019;36(2):96-109. http://dx.doi.org/10.1016/j.hipert.2019.01.001

Díaz Molina M, Herrera Preval Y, Matéu López L. Adherencia al tratamiento antihipertensivo en pacientes del municipio San Miguel del Padrón. Rev Cubana Farm. 2014;48(4):588-97.

Kripalani S, Yao X, Haynes RB. Interventions to enhance medication adherence in chronic medical conditions: a systematic review. Arch Intern Med. 2007;167(6):540-50. https://doi.org/10.1001/archinte.167.6.540

Guarín-Loaiza GM, Pinilla-Roa AE. Adherencia al tratamiento antihipertensivo y su relación con la calidad de vida en pacientes de dos hospitales de Bogotá, D.C. 2013-2014. Rev Fac Med. 2016;64(4):651. https://doi.org/10.15446/revfacmed.v64n4.52217

Varleta P, Akel C, Acevedo M, Salinas C, Pino J, Opazo V, et al. Prevalencia y determinantes de adherencia a terapia antihipertensiva en pacientes de la Región Metropolitana. Rev Méd Chile. 2015;143(5):569-76. http://dx.doi.org/10.4067/S0034-98872015000500003

Perseguer-Torregrosa Z, Orozco-Beltrán D, Gil-Guillen VF, Pita-Fernandez S, Carratalá-Munuera C, Pallares-Carratalá V, et al. Magnitude of pharmacological nonadherence in hypertensive patients taking antihypertensive medication from a community pharmacy in Spain. J Manag Care Spec Pharm. 2014;20(12):1217-25. https://doi.org/10.18553/jmcp.2014.20.12.1217

Natarajan N, Putnam W, Van Aarsen K, Lawson KB, Burge F. Adherence to antihypertensive medications among family practice patients with diabetes mellitus and hypertension. Can Fam Physician. 2013;59(2):e93-100.

Caro JJ, Speckman JL, Salas M, Raggio G, Jackson JD. Effect of initial drug choice on persistence with antihypertensive therapy: The importance of actual practice data. CMAJ. 1999;160(1):41-6.

Fernandez-Arias M, Acuna-Villaorduna A, Miranda JJ, Diez-Canseco F, Malaga G. Adherence to pharmacotherapy and medication-related beliefs in patients with hypertension in Lima, Peru. PLoS ONE. 2014;9(12): e112875. https://doi.org/10.1371/journal.pone.0112875

Castaño-Castrillón JJ, Echeverri-Rubio C, Giraldo-Cardona JF, Maldonado-Mora Á, Melo-Parra J, Meza-Orozco GA, et al. Treatment adherence of hypertensive patients’ being attended by Assbasalud ESE, Manizales (Colombia) 2011. Rev Fac Med. 2012;60(3):179-97.

Rosas-Chavez G, Romero-Visurraga CA, Ramirez-Guardia E, Málaga G. El grado de alfabetización en salud y adherencia al tratamiento en pacientes con hipertensión arterial en un hospital de Lima, Perú. Rev Peru Med Exp Salud Pública. 2019;36(2):214-21. https://doi.org/10.17843/rpmesp.2019.362.4279

Kunert J. Adherencia al tratamiento antihipertensivo en pacientes ambulatorios de un hospital urbano. Rev Virtual Soc Parag Med Int. 2015;2(2):43-51. https://doi.org/10.18004/rvspmi/2312-3893/2015.02(02)43-051

Al-Noumani H, Wu JR, Barksdale D, Sherwood G, AlKhasawneh E, Knafl G. Health beliefs and medication adherence in patients with hypertension: A systematic review of quantitative studies. Patient Educ Couns. 2019;102(6): 1045-1056. https://doi.org/10.1016/j.pec.2019.02.022

Rodríguez López MR, Varela MT, Rincón-Hoyos H, Velasco MM, Caicedo DM, Méndez F, et al. Prevalencia y factores asociados a la adherencia al tratamiento no farmacológico en pacientes con hipertensión y diabetes en servicios de baja complejidad. Rev Fac Nac Salud Pública. 2015;33(2):192-9. https://doi.org/10.17533/udea.rfnsp.v33n2a06

DiMatteo MR, Giordani PJ, Lepper HS, Croghan TW. Patient adherence and medical treatment outcomes: a meta-analysis. Med Care. 2002;40(9):794-811. https://doi.org/10.1097/00005650-200209000-00009

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.