Compromiso renal y digestivo en infecciones por COVID-19

Palabras clave: SRAG-CoV-2,COVID-19, enfermedades renales, infecciones por coronavirus, enfermedades gastrointestinales.

Resumen

La infección por el síndrome respiratorio agudo severo (SARS-CoV-2) ha causado una de las emergencias epidemiológicas más grandes de los últimos 10 años y sus efectos patológicos son aún estudiados. Por lo anterio, resulta importante describir los mecanismos asociados al compromiso renal y digestivo en la infección por SARS-CoV-2. Los mecanismos patológicos en tejido renal y en intestino causados por la infección por SARS-CoV-2 son propios del tropismo viral por células de estos sistemas y de los mecanismos citopáticos de etapa lítica de la infección, con una liberación continua de viriones que favorece la generación de un entorno inflamatorio con la consecuente secreción descontrolada de citoquinas proinflamatorias que conducen a la infección entérica del intestino y a las alteraciones en el riñón.

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Publicado
2020-05-15
Cómo citar
1.
Navarro-Quiroz RC, Atencio-Ibarra L, Herrera Usuga JC, Osorio Ospina LM, Navarro Quiroz KF, Potes Rodriguez YC, Gómez Escorcia L, Aroca Martínez G, Navarro-Quiroz E. Compromiso renal y digestivo en infecciones por COVID-19. Rev. Colomb. Nefrol. [Internet]. 15 de mayo de 2020 [citado 26 de noviembre de 2020];7(Supl.2). Disponible en: https://revistanefrologia.org/index.php/rcn/article/view/427