Compromiso renal y digestivo en infecciones por COVID-19

Palabras clave: SARS-CoV-2,COVID-19, Nefropatía por coronavirus, patofisiología de la infección viral por SARS-CoV-2,Síntomas gastrointestinales .

Resumen

La infección por el Síndrome Respiratorio Agudo Severo (SARS-CoV-2) a causado una de las emergencias epidemiológicas más grande de los últimos 10 años y su efecto patológicos son aún estudiados.

Por lo anteriormente mencionado resulta importante describir los mecanismos asociados al compromiso renal y digestivo en la infección por SARS-CoV-2.

Los mecanismos patológicos en tejido renal y en intestino causado por la infección por SARS-CoV-2 son propias del tropismo viral por células de estos sistemas y de los mecanismos citopáticos de etapa lítica de la infección, con una liberación continua de viriones que favorece la generación de un entorno inflamatorio con la consecuente secreción descontrolada de citoquinas proinflamatorias que conducen infección entérica el intestino y a las alteraciones en el riñón.

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Biografía del autor/a

Roberto C. Navarro-Quiroz, CMCC-Centro de Matemática, Computação e Cognição, Laboratório do Biología Computacional e Bioinformática–LBCB, Universidade Federal do ABC, Sao Paulo, 01023, Brazil
                           

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Publicado
2020-05-15
Cómo citar
1.
Navarro-Quiroz RC, Atencio-Ibarra L, Herrera Usuga JC, Osorio Ospina LM, Navarro Quiroz KF, Potes Rodriguez YC, Gómez Escorcia L, Aroca Martínez G, Navarro-Quiroz E. Compromiso renal y digestivo en infecciones por COVID-19. Rev. Colomb. Nefrol. [Internet]. 15 de mayo de 2020 [citado 4 de junio de 2020];7(Supl 2). Disponible en: https://revistanefrologia.org/index.php/rcn/article/view/427
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Artículo de revisión