Primary glomerulonephritis in children attending a Referral Center in the Colombian Caribbean Region
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Aroca Martínez G, Polo Castillo A, Bonfantti AC, González Torres HJ, Padilla Galindo H, Depine S Ángel. Primary glomerulonephritis in children attending a Referral Center in the Colombian Caribbean Region. Rev. Colomb. Nefrol. [Internet]. 2015 Jan. 1 [cited 2024 May 20];2(1):12-8. Available from:


Introduction: Primary glomerulonephritis are diseases that affect the structure and function of the glomerulus. For proliferative glomerulopathies, it has been observed that for IgA and IgM mesangial GN, they are the ones that mostly evolve to end-stage renal failure, followed by membranous-proliferative or mesangiocapillar GN. The clinical manifestation of GN is the result of the combination of hematuria, proteinuria and the presence of acute or chronic renal failure.

Material and methods: Medical records were reviewed. They were collected in a database of all biopsies performed from 2008 to 2014. An ?² was used to establish associations between variables (? = 95%). For the differences among proportions Student’s t or U-Mann-Whitney were used.

Results: 146 (88%) patients who had complete data were selected. The mean age was 8 ± 4 years old for both sexes. No significant difference was found between gender by age (p? 0.05), nor was there an association between gender and age (p? 0.05). The predominant NGs with the highest prevalence were Proliferative Mesangial and IgA Nephropathy. NGs by Thin Basal Membrane, Nephropathy by C3 and Cq were not present in male patients. The most prevalent syndromic picture was the Nephrotic Syndrome (58%).

Conclusions: The existence of this registry of renal biopsies is the basis for the creation of the Registry of Glomerulopathies in children in Colombia, whose data are necessary to establish programs for the treatment and prevention of glomerular diseases in our country in order to decrease its progression.
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