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Abstract
Systemic sclerosis (SS), is characterized by the presence of thickening and hardening of the skin (from the Greek "sclero"), it has forms of limited and diffuse manifestation. It is chronic in pattern and manifests with vascular dysfunction and severe systemic connective fibrosis. Sclerodermic renal crisis (CRE) is the severe manifestation in the kidney, and is characterized by:
- Malignant hypertension, of sudden onset associated with increased plasma renin activity. There is a clinical variant, which presents with normotension, which has a worse prognosis. (UTAH)
- Acute Renal Failure (ARF).
- Proteinuria in the non-nephrotic range. Microscopic hematuria and casts are uncommon.
Next, we are going to report the presentation of a case of sclerodermic renal crisis (CRE), in a 60-year-old female patient, who was admitted to our institution with a condition characterized by severe arterial hypertension, severe glomerular filtration drop, microhematuria and proteinuria; which received medical treatment, but due to the persistence of signs and symptoms, it was decided to perform a renal biopsy puncture, which confirmed the diagnosis.
References
Guillevin L, Bérezné A, Seror R, Teixeira L, Pourrat J, Mahr A, et al. Scleroderma renal crisis: a retrospective multicentre study on 91 patients and 427 controls. Rheumatology. 1 de marzo de 2012;51(3):460-7.
Mouthon L, Bérezné A, Bussone G, Noël L-H, Villiger PM, Guillevin L. Scleroderma Renal Crisis: A Rare but Severe Complication of Systemic Sclerosis. Clin Rev Allergy Immunol. 1 de abril de 2011;40(2):84-91.
Abbott KC, Trespalacios FC, Welch PG, Agodoa LYC. Scleroderma at end stage renal disease in the United States: patient characteristics and survival. J Nephrol. junio de 2002;15(3):236-40.
Penn H, Howie AJ, Kingdon EJ, Bunn CC, Stratton RJ, Black CM, et al. Scleroderma renal crisis: patient characteristics and long-term outcomes. QJM Int J Med. 1 de agosto de 2007;100(8):485-94.
Alenzi F. Scleroderma renal crisis: Importance of knowing and differentiating in emergency unit. :3.
Trimarchi H, Calvo M, Malvar A, Alberton V, Lococo B, Greloni G, et al. Enfermedades Glomerulares. Buenos Aires: El Edén del Hipocampo; 616-621 p.
Steen VD, Costantino JP, Shapiro AP, Medsger TA. Outcome of Renal Crisis in Systemic Sclerosis: Relation to Availability of Angiotensin Converting Enzyme (ACE) Inhibitors. Ann Intern Med. 1 de septiembre de 1990;113(5):352-7.
Cannon PJ, Hassar M, Case DB, Casarella WJ, Sommers SC, LeROY EC. THE RELATIONSHIP OF HYPERTENSION AND RENAL FAILURE IN SCLERODERMA (PROGRESSIVE SYSTEMIC SCLEROSIS) TO STRUCTURAL AND FUNCTIONAL ABNORMALITIES OF THE RENAL CORTICAL CIRCULATION. Medicine (Baltimore). enero de 1974;53(1):1–46.
Donohoe JF. Scleroderma and the kidney. Kidney Int. febrero de 1992;41(2):462-77.
Steen VD. Scleroderma renal crisis. Rheum Dis Clin North Am. mayo de 2003;29(2):315-33.
Woodworth TG, Furst DE. Timely renal transplantation for scleroderma end-stage kidney disease patients can improve outcomes and quality of life. Ann Transl Med. 23 de enero de 2019;7(3):22.
Afección renal en la esclerosis sistémica [Internet]. [citado 11 de septiembre de 2020]. Disponible en: https://www.reumatologiaclinica.org/es-pdf-S1699258X06731035
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