Kidney failure in cirrhosis: review of the literature
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acute renal failure
liver cirrhosis
hepatorenal syndrome

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Almanza Hurtado AJ, Rodríguez Yánez T, Martínez-Ávila MC, Imbeth Acosta P. Kidney failure in cirrhosis: review of the literature. Rev. Colomb. Nefrol. [Internet]. 2022 Feb. 14 [cited 2022 May 18];9(1):e531. Available from:


Introduction: During the cirrhotic patient’s disease, renal failure is a poor prognostic event.

Purpose: Knowing the risk factors for AKI in these patients given by the presence of infectious processes, loss of fluids due to hemorrhage, gastrointestinal or kidney, and nephrotoxic agents are essential for initiating therapeutic measures and prophylactic actions.

Methodology: A bibliographic search was carried out in the PubMed, EMBASE, Scopus and academic Google databases, using the terms MeSH acute renal failure, creatinine, liver cirrhosis, hepatorenal syndrome. Original articles, meta-analyzes, case reports, case series and literature reviews were obtained, choosing 16 documents for the preparation of this review.

Results: The new criteria defined by the International Ascites Club (AKI-IAC), which eliminate urinary out put, are determined by an increase in serum creatinine?0.3 mg / dL in less than 48 hours and improve the prognosis, allowing timely interventions.

Conclusions: Creatinine continues to be the most widely used biomarker in AKI, even in cirrhotic patients, despite its multiple limitations. A dynamic criterion modified from the AKIN criteria becomes the gold standard for the diagnosis of AKI in cirrhosis.
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