Keywords
Ambulatory Blood Pressure Monitoring
Haemodialysis
Hypertension
Twice-weekly haemodialysis
How to Cite
Abstract
Introduction: Chronic kidney disease (CKD) poses a significant global health challenge and is often associated with hypertension (HTN) and cardiovascular diseases (CVD). Ambulatory blood pressure monitoring (ABPM) is a promising approach for precise blood pressure assessment, particularly in patients with chronic kidney disease. This study aimed to evaluate the efficacy of ABPM in managing blood pressure (BP) in patients with end-stage renal disease (ESRD) undergoing haemodialysis.
Objective: This study aimed to compare the effectiveness of ambulatory blood pressure monitoring as an adjunct to routine blood pressure management in achieving optimal blood pressure control among patients on haemodialysis. The secondary objectives included a study of the variation in systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean arterial pressure (MAP) at baseline and at 3 months, along with variations of night-time and daytime blood pressure in haemodialysis patients.
Materials and methods: A comparative prospective study was conducted, enrolling 62 patients with chronic kidney disease undergoing haemodialysis twice weekly. ABPM was added to the routine blood pressure monitoring in the experimental group, whereas only routine blood pressure monitoring was conducted in the control group. Demographic data, pre- and post-haemodialysis blood pressure, ABPM recordings, and laboratory parameters were collected. Data analysis included descriptive statistics, t-tests, and chi-square tests.
Results: The mean ages of participants in the experimental and control groups were 52 ± 16.7 years and 47.9 ± 14.3 years, respectively. The study found that ABPM significantly improved blood pressure control compared with routine monitoring at the end of 3 months. Statistically significant differences were observed in mean systolic blood pressure (140 ± 12.7 vs. 151 ± 17.6, P=0.006), diastolic blood pressure (84 ± 6.2 vs. 89 ± 8.6, P=0.011) and mean arterial pressure (106 ± 7 vs. 110 ± 8.4, P=0.046) between the two groups.
Conclusion: Our study emphasizes ABPM's vital role in improving blood pressure management in CKD patients on haemodialysis and also in identifying the nuances of blood pressure variation in this vulnerable population.
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