Keywords
COVID-19
Intensive care units
How to Cite
Abstract
Methodology: Retrospective cohort study, with convenience sampling during the period from April 2020 to March 2021, through the review of medical records data. Inclusion criteria were; patients ? 18 years old, with a diagnosis of COVID-19 infection, who were admitted to ICU with normal renal function and developed AKI during their stay in ICU. Exclusion criteria were; patients who developed AKI prior to ICU admission, patients with chronic kidney disease with and without dialysis.
Results: A total of 177 medical records that met the inclusion and exclusion criteria were evaluated. The mean age was 57.2±13.2 years, 145 (81.4%) were male; comorbidities were: obesity 112(63.3%), arterial hypertension 55 (31.1%) and diabetes mellitus 30(16.9%); the most frequent cause of AKI was hypoperfusion 93%. 83 participants (46.8%) received dialytic support in the intermittent hemodialysis modality. In-hospital mortality was 151 (85.3%) and higher in the group with stage 3 AKI: 109 (72.2%). The increase in ferritin level (OR: 4.42 (IC95% 4.31-18.44), p<0,001) and APACHE score (OR: 2.41 (IC95% 1.18-4.93), p<0,016), as well as the decrease in PaO2/FiO2 level (OR: 0.85 (IC95% 0.52-0.92), p<0.042) , were related to mortality.
Conclusions: AKI in ICU patients with COVID-19 infection has a high mortality and the related factors were the increase in APACHE II score and ferritin level, as well as the decrease in PaO2/FiO2 level.
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