Characterization of subclinical chronic kidney disease in Chile
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Keywords

kidney diseases; renal insufficiency, chronic kidney disease, asymptomatic diseases, early diagnosis, glomerular filtration rate, albuminuria

How to Cite

1.
Castillo AA, Castillo Montes M. Characterization of subclinical chronic kidney disease in Chile. Rev. Colomb. Nefrol. [Internet]. 2022 Sep. 2 [cited 2022 Sep. 24];9(2). Available from: https://revistanefrologia.org/index.php/rcn/article/view/585

Abstract

Introduction: subclinical chronic kidney disease (CKDs), performing screening in at-risk populations, is poorly characterized in Chile. Its knowledge would contribute to better management and early treatment, mitigating its consequences. Objective: to describe the epidemiological and clinical characteristics of the population with CKDs in Chile. Materials and methods: cross-sectional descriptive study in a population of 1,032 subjects from three regions of Chile; Coquimbo (n=902), Metropolitana (n=70) and De Los Ríos (n=60), from cardiovascular programs, other Primary Care programs and direct relatives of dialysis patients. Informed consent, survey, physical examination (blood pressure, weight and height) and laboratory tests (creatinine and albumin/creatinine urinary ratio) were performed. CKD was defined by KDOQI-2012 guideline and Glomerular Filtration Rate according to MDRD formula. Albuminuria by relation albumin/creatinine of first urination (mg/g). eVFG <60 ml/min and/or Albuminuria ? 30 mg/g, defined CKDs. Frequencies and comparisons were determined (chi-square, t student and ANOVA), with a significance level of p<0.05. Results: 205 subjects (19.9%) presented CKDs, being significantly more frequent in ?65 years (35.7%), who achieved elementary school studies (26.6%), domestic service workers (44%), retired workers (40%), having a family member on dialysis (24.6%) and insulin-requesting diabetics (70.6%). In the ?65 year-old group, there was a significantly lower frequency of CKDs in those who performed physical activity, compared to sedentary (48.8%). The higher the intensity of hypertension and pulse pressure (PP), the higher the frequency of CKDs. Conclusions: These data provide useful epidemiological information for the programming of better detection strategies for CKDs in Chile

https://doi.org/10.22265/acnef.9.2.585
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