Quality of Life and Associated Risk Factors in Hemodialysis: Perspective from a Center in the Dominican Republic


Quality of Life
Risk factors
Dominican Republic

How to Cite

Jimenez Ramirez R, Lopez Gonzalez FE, Rivera Martínez AR, Rodríguez Liriano CG, Lara Pichardo JN, Acosta Díaz Y. Quality of Life and Associated Risk Factors in Hemodialysis: Perspective from a Center in the Dominican Republic. Rev. Colomb. Nefrol. [Internet]. 2022 Sep. 12 [cited 2024 Jul. 16];9(2). Available from: https://revistanefrologia.org/index.php/rcn/article/view/581


Background: Chronic kidney disease has an overall prevalence of 10?%. It can progress to a condition called end-stage renal disease. Therapies such as hemodialysis are necessary at this stage. Our study aims to measure the quality of life of patients on hemodialysis.

Methods: We conducted an observational, cross-sectional study with 81 patients. Data was collected using a survey that included sociodemographic variables, the Center for Epidemiological Studies Depression Screening Index (CES-D), and the Kidney Disease Quality of Life (KDQOL-SF36). Data were analyzed using the software Epi Info™ 7.2, t-test, ANOVA, and correlation coefficient.

Results: The severity of symptoms is more significant in the female sex than in males (65.7117 vs. 74.2874). All of the components of the KDQOL-SF36 showed a negative correlation with the CES-D. Household income had a mild positive correlation with the scale (r = 0.2608, p = 0.0229). Physical activity was shown to be associated with the physical component of the scale (41.6346 vs. 35.7365, p = 0.0412). Patients with partners were associated with higher quality of life scores than single patients (53.6585 vs. 42.6783, p = 0.0348).

Conclusion: This is the first study conducted in the Dominican Republic to analyze the variables affecting the quality of life in patients in hemodialysis units. The severity of the symptoms increased in female patients, and patients without a partner are associated with worse quality of life scores.



D?browska-Bender M, Dykowska G, ?uk W, Milewska M, Staniszewska A. The impact on quality of life of dialysis patients with renal insufficiency. Patient Prefer Adherence. 2018;12:577–583. https://doi.org/10.2147/PPA.S156356

Bikbov B, Purcell CA, Levey AS, Smith M, Abdoli A, Abebe M, et al. Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020 Feb;395(10225):709-33.

Murdeshwar HN, Anjum F. Hemodialysis. StatPearls Publishing; 2021. Available from: http://www.ncbi.nlm.nih.gov/books/NBK563296/

Zhang L, Guo Y, Ming H. Effects of hemodialysis, peritoneal dialysis, and renal transplantation on the quality of life of patients with end-stage renal disease. Rev Assoc Med Bras. 2020;66:1229–1234. https://doi.org/10.1590/1806-9282.66.9.1229

WHOQOL. Measuring Quality of Life [Internet]. [cited 2021 Oct 3]. Available from: https://www.who.int/tools/whoqol

Carrillo-Algar AJ, Torres-Rodríguez GA, Leal-Moreno CS, Hernández Zambrano SM. Escalas para evaluar la calidad de vida en personas con enfermedad renal crónica avanzada: Revisión integrativa. Rev Enfermed Nefrolog. 2018 Oct-Dec;21(4):334-47 https://doi.org/10.4321/S2254-28842018000400003

Mapes DL, Lopes AA, Satayathum S, Mccullough KP, Goodkin DA, Locatelli F, et al. Health-related quality of life as a predictor of mortality and hospitalization: The Dialysis Outcomes and Practice Patterns Study (DOPPS). Kidney Int. 2003 Jul 1;64(1):339–49. https://doi.org/10.1046/j.1523-1755.2003.00072.x

Oficina nacional de estadística. Estimación de la Canasta Básica y las Líneas de Pobreza; 2012.

Ministerio de Economía, Planificación y Desarrollo (MEPyD). Boletín de estadísticas oficiales de pobreza monetaria en la República Dominicana año 6 • no 8 [Internet]. [cited 2021 Oct 3]. Available from: https://mepyd.gob.do/publicaciones/boletin-pobreza-monetaria-a6-no8

Radloff LS. The CES-D scale: A self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1:385-401. https://doi.org/10.1177/014662167700100306

Ma TK, Li, PK. Depression in dialysis patients. Nephrology, 2016;21:639–646. https://doi.org/10.1111/nep.12742

Zúñiga SMC, Dapueto PJ, Müller OH, Kirsten LL, Alid AR, Ortiz ML. Evaluación de la calidad de vida en pacientes en hemodiálisis crónica mediante el cuestionario «Kidney Disease Quality of Life (KDQOL-36)». Rev Med Chil. 2009 Feb;137(2):200-7. https://doi.org/10.4067/S0034-98872009000200003

Pretto CR, Winkelmann ER, Hildebrandt LM, Barbosa DA, Colet C de F, Stumm EMF. Quality of life of chronic kidney patients on hemodialysis and related factors. Rev Latino-Am Enfermagem [Internet]. 2020 Jul 15 [cited 2022 Jan 22];28. https://doi.org/10.1590/1518-8345.3641.3327

Capote Leyva E, Argudín Selier R, Mora González S, Capote Pereira L, Leonard Rupalé I, Moret Hernández Y. Evaluación de la calidad de vida relacionada con salud en pacientes en hemodiálisis periódica utilizando el KDQOL-SFTM. MediSur. 2015 Aug;13(4):508-16.

Guerra-Guerrero V, Sanhueza-Alvarado O, Cáceres-Espina M. Quality of life in people with chronic hemodialysis: association with sociodemographic, medical-clinical and laboratory variables. Rev Latino-Am Enfermagem. 2012 Oct;20:838-46. https://doi.org/10.1590/S0104-11692012000500004

Santos PR, Franco Sansigolo Kerr LR. Clinical and laboratory variables associated with quality of Ufe in Brazilian haemodialysis patients: a single-centre study. Rev Med Chil. Oct 2008;136(10):1264-71. https://doi.org/10.4067/S0034-98872008001000005

Mahato SKS, Apidechkul T, Sriwongpan P, Hada R, Sharma GN, Nayak SK, et al. Factors associated with quality of life among chronic kidney disease patients in Nepal: a cross-sectional study. Health Qual Life Outcomes. 2020;18(1):207. https://doi.org/10.1186/s12955-020-01458-1

Sathvik BS, Parthasarathi G, Narahari MG, Gurudev KC. An assessment of the quality of life in hemodialysis patients using the WHOQOL-BREF questionnaire. Indian J Nephrol. 2008 Oct;18(4):141. https://doi.org/10.4103/0971-4065.45288

Blake C, Codd MB, Cassidy A, O’Meara YM. Physical function, employment and quality of life in end-stage renal disease. J Nephrol. 2000 Apr;13(2):142–9.

RAND. Kidney Disease Quality of Life Instrument (KDQOL) [Internet]. [cited 2021 Oct 3]. Available from: https://www.rand.org/health-care/surveys_tools/kdqol.html

Bayoumi M, Al Harbi A, Al Suwaida A, Al Ghonaim M, Al Wakeel J, Mishkiry A. Predictors of quality of life in hemodialysis patients. Saudi J Kidney Dis Transpl. 2013;24(2):254-259. https://doi.org/10.4103/1319-2442.109566

Chen JY, Wan EYF, Choi EPH, Chan AKC, Chan KHY, Tsang JPY, et al. The Health-Related Quality of Life of Chinese Patients on Hemodialysis and Peritoneal Dialysis. Patient. 2017;10(6):799-808. https://doi.org/10.1007/s40271-017-0256-6

Pan CW, Wu Y, Zhou HJ, Xu BX, Wang P. Health-Related Quality of Life and Its Factors of Hemodialysis Patients in Suzhou, China. Blood Purif. 2018;45(4):327-333. https://doi.org/10.1159/000485962

Chiang C-K, Peng Y-S, Chiang S-S, Yang C-S, He Y-H, Hung K-Y. HEALTH-related quality of life of hemodialysis patients in Taiwan: A multicenter study. Blood Purif 2004;22:490-8. https://doi.org/10.1159/000081730

Anees M, Batool S, Imtiaz M, Ibrahim M. Socio-economic factors affecting quality of life of Hemodialysis patients and its effects on mortality. Pak J Med Sci. 2018;34(4):811-816. https://doi.org/10.12669/pjms.344.15284

Al-Jumaih A, Al-Onazi K, Binsalih S, Hejaili F, Al-Sayyari A. A study of quality of life and its determinants among hemodialysis patients using the KDQOL-SF instrument in one center in Saudi Arabia. Arab J Nephrol Transplant. 2011;4(3):125-130. https://doi.org/10.4314/ajnt.v4i3.71024

Neumann D, Mau W, Wienke A, Girndt M. Peritoneal dialysis is associated with better cognitive function than hemodialysis over a one-year course. Kidney Int. 2018;93(2):430-8. https://doi.org/10.1016/j.kint.2017.07.022

Lu R, Estremadoyro C, Chen X, Zhu M, Ribeiro LC, Yan Y, et al. Hemodialysis versus peritoneal dialysis: an observational study in two international centers. Int J Artif Organs. 2017. https://doi.org/10.5301/ijao.5000656

Doan KVD, Nguyen HTM, Nguyen NTH, Dang KC, Yang SH, Duong TV. Associations of Sociodemographic, Clinical and Biochemical Parameters with Healthcare Cost, Health- and Renal-Related Quality of Life in Hemodialysis Patients: A Clinical Observational Study. Int J Environ Res Public Health. 2020;17(18):6552. https://doi.org/10.3390/ijerph17186552

Anu V, Pushpa P, Kumar SS. Quality of life of patients undergoing hemodialysis at B. P. Koirala institute of health sciences. J Manmohan Memorial Institute Health Sci. 2014;1(20):19–25. https://doi.org/10.3126/jmmihs.v1i2.9904

Al Wakeel J, Al Harbi A, Bayoumi M, Al-Suwaida K, Al Ghonaim M, Mishkiry A. Quality of life in hemodialysis and peritoneal dialysis patients in Saudi Arabia. Ann Saudi Med. 2012;32(6):570-574. https://doi.org/10.5144/0256-4947.2012.570

Zouari L, Omri S, Turki S, Maalej M, Charfi N, Thabet JB, et al. Quality of life in chronic hemodialysis patients: about 71 cases. Tunis Med. 2016;94(1):40-45.

Alencar SBV, de Lima FM, Dias LDA, Dias VDA, Lessa AC, Bezerra JM, et al. Depression and quality of life in older adults on hemodialysis. Braz J Psychiatry. 2020;42(2):195-200. https://doi.org/10.1590/1516-4446-2018-0345

Donia AF, Zaki NF, Elassy M, Elbahaey W. Study of depression and quality of life among hemodialysis patients: an Egyptian experience. Int Urol Nephrol. 2015;47(11):1855-1862. https://doi.org/10.1007/s11255-015-1091-0

Bornivelli C, Aperis G, Giannikouris I, Paliouras C, Alivanis P. Relationship Between Depression, Clinical and Biochemical Parameters in Patients Undergoing Haemodialysis. J Renal Care. 2012;38(2):93–7. https://doi.org/10.1111/j.1755-6686.2012.00259.x

Villanego F, Naranjo J, Vigara LA, Cazorla JM, Montero ME, García T, et al. Impacto del ejercicio físico en pacientes con enfermedad renal crónica: revisión sistemática y metaanálisis. Nefrología. 2020 May 1;40(3):237-52. https://doi.org/10.1016/j.nefro.2020.01.002

Manfredini F, Mallamaci F, D’Arrigo G, Baggeta R, Bolignano D, Torino C, et al. Exercise in Patients on Dialysis: A Multicenter, Randomized Clinical Trial [published correction appears in J Am Soc Nephrol. 2018 Jul;29(7):2028]. J Am Soc Nephrol. 2017;28(4):1259-1268. https://doi.org/10.1681/ASN.2016030378

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.




Download data is not yet available.