Efficacy and safety of chloroquine, hydroxychloroquine and azithromycin in patients with COVID-19: Summary of evidence
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Keywords

COVID-19, hydroxychloroquine, azithromycin, adverse drug event, prophylaxis

How to Cite

1.
Chacón Acevedo K, Pinzón C, Barrera A, Low Padilla E, Yomayusa González N. Efficacy and safety of chloroquine, hydroxychloroquine and azithromycin in patients with COVID-19: Summary of evidence. Rev. Colomb. Nefrol. [Internet]. 2020 Jun. 11 [cited 2022 Aug. 13];7(Supl.2). Available from: https://revistanefrologia.org/index.php/rcn/article/view/469

Abstract

Introduction: The COVID-19 disease is a health emergency; treatment has not yet been proven.

Objective: To present the available evidence of efficacy and safety of the use of hydroxychloroquine and azithromycin in the prophylaxis and management of patients with COVID-19.

Methods: A rapid literature review was performed; we consulted Medline, scopus and pubmed databases.

Results: Eleven publications were included including rapid literature reviews, observational studies, and clinical trials. No data were found studying prophylaxis with hydroxychloroquine and azithromycin for SARS-CoV-2. Reports of adverse events include episodes of emesis, abdominal pain, nausea, diarrhea, rash, and itching.

Conclusions: The evidence collected suggests that the use of hydroxychloroquine and azithromycin in patients with COVID-19, could abnormal electrocardiogram and increased risk of mortality in-hospital. The effectiveness remains unclear.

https://doi.org/10.22265/acnef.7.Supl.2.469
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No national or foreign publication may partially or totally reproduce or translate Revista Colombiana de Nefrología articles or abstracts without prior written permission from the journal’s Editorial Board.

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