Living-donor kidney transplant in Colombia
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Living Donor Kidney
Health Promoter
Health Provider Institution
Single Antigen

How to Cite

García García Álvaro, Rodelo J. Living-donor kidney transplant in Colombia. Rev. Colomb. Nefrol. [Internet]. 2015 Jan. 1 [cited 2022 Jan. 21];2(1):41-6. Available from:


The best alternative for the treatment of patients with CKD-5 is renal transplantation; unfortunately, it has declined significantly, not only in Colombia but worldwide. Among the proposed medical and surgical approaches to extend this treatment, marginal donors were used at the beginning, but soon they were not enough due to the huge increase in the number of people in the waiting lists, many of them dying waiting for an organ. Given the excellent results of living donors, with graft survival approaching 90% at 10 years of follow up, explained by an increase in HLA compatibility, ease of planning the optimal moment for the transplantation, lower delayed graft function andcosts, in addition to a minimum peri-operative risk for the donor as evidenced by Hartman et al, with a mortality rate of 3.1 x 10,000, when laparoscopic and pain control techniques are used, renal transplantation with living donors becomes an acceptable alternative worldwide. Clear policies for patient and donor follow-up after nephrectomy, in which the donor loses 35% of his kidney function, are mandatory these protocols. Initial follow-up studies of living donors showed a similar relative risk of hypertension, proteinuria and CKDcimpared to the general population, which facilitated this medical practice; nevertheless, in the last five years the convenience of this practice is in doubt by some authors due to a significant increase in the relative risk of diabetes mellitus, hypertension and cardiovascular disease, compared with healthy donors.This has been shown by Muzale et al., in a cohort of 96 217 living donors compared to 20 024 persons of NHANES III: an increase of CKD in living donors compared with healthy patients at 10 and 15 years; the relative risk at 15 years was 30.8 and 3.9 x 10,000, respectively. Regarding female donors in reproductive age, Amit. X. puts into question this type of donor as he found a significant increase in hypertension and preeclampsia during pregnancy in these women (11%) when compared to healthy women (5%). That is why we ask the health providers and transplant groups a comprehensive assessment, with fully defined protocols to evaluate, prevent and reduce the risks of this excellent treatment modality for patients with stage 5 CKD.
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1. IbrahinHN, Foley R, Tan L, Rogers T, Bailey RF, Guo H, et al. Long term consequences of kidney donation. N Engl J Med 2009;360:459-69.

2. Charpentier B, Durrbach A, Transplantation: pre-emptive kidney transplantation- perfect, but when?Nat. Rev Nephrol 2011;7:550-1.

3. Harvat LD, ShriffSZ, Garg AX. Global trends in the rates of iving kidney donation.KidneyInt. 2009;75:1088-98.

4. Coordinacion Nacional/red de donación y trasplantes (,

5. New OPTN requirements and resources for living donor kidney transplant programs.Organ Procurement and Transplantation Network (OPTN). Prog. Transplant 2013; Jun23(2):117.

6. KasiskeBL, IsraniAK, SnyderJJ, Camarena A; et al.Design considerations and feasibility for a clinical trial to examine coronary screening before kidney transplantation (Cost). AM J kid Dis 2011; Jun 57(6):908-16.

7. Wong G, Chapman JR, Cancers after renal transplantation. Transplantation reviews 22 (2008)141-149.

8. Ponticelli C, Cucchiari D, Bencini P. Skin cancer in kidney transplant recipients.J Nephrol 2014 august 27(4)385-94.

9. Kashtan CE, Segal Y. Genetic disorders or glomerular basement membranes. NeprhonClinPract. 2011;118:c9-c18.

10. Hass M, et al. Alport Syndrome and thin glomerular basement membrane nephropathy: a practical approach to diagnosis. Arch Pathol lab med. 2009;133:224-232.

11. Consugar MB, Wong WC, Lundquist PA, Rossetti VJ, KublyVJ, Walker DL, et al. Characterization of large rearrangements in autosomal dominant polycystic kidney disease and the PKD1/TSC2 contiguous gene syndrome. Kidney International 2008;74:1468-1479.

12. Qi XP, Du ZF, Ma JM, Chen XL, Zhang Q, Fei J, et al. Genetic diagnosis of autosomal dominant polycystic kidney disease by targeted capture and next-generation sequencing: utility and limitation. Gene 2013 Mar 1;516(1):93-100.

13. Golbert WA, Appel GB, Hariharan S. Recurrent glomerulonephritis after renal transplantation: An unsolved problem. Clin J Am SocNephrol. 2008 May; 3(3):800-7.

14. Pontecelly C, Moroni G, Glassock.De novo glomerular diseases after renal transplantation.Clin J Am SocNeprol, 2014, Aug 7, 9(8):1479-87.

15. Hartmann A, Fauchald P, Westli L, BrekkeIB, Holdaas H. The risk of living kidney Donation. Nephrol dial transplant 2003;18(5)871.

16. Poqqio ED, Braun WE, Davis C. The science of stewardship: due diligence for kidney donors and kidney function in living kidney donation – evaluation, determinants, and implications for outcomes. Clin J Am SocNephrol 2009; Oct 4(10):1677-84.

17. Leichtman A, Abecassis M, Barr M, Charlton M, Cohen D, ConferD, et al. Living kidney donor follow- up: state of the art and future directions, conference summary and recommendations. AJ Transplant. 2011 Dec; 11(12):2561-8.

18. Oppenheiner Hospital Clinic – Barcelona ( 19. Base de datos del grupo de trasplantes Nefron, U de A y HSVP de Medellín (

20. Thomson DA, Muller E, Kahn D. Laparoscopic kidney donation- giving in the best way possible. S Afr J Surg. 2014 Jun 6;52(2):34-5.

21. Dunn TB, Browne BJ, Gillingham KJ, Kandaswamy R, Humar A, Payne WD et al. Selective retransplant after Graft loss to no adherence: Success with a second chance. Am J Transplant 2009 (9)6:1257.

22. Ibrain HN, KuKla A, Cordner G, Bailey R, Gillingham K, MatasAJ. Diabetes after kidney Donation. A J Transplant. 2010, Feb; 10(2):331-337.

23. Lentine KL, Schnitzler MA, Xiao H, Saab G, Salvalaggio PR, Axelrod D, et al. Racial variation in medical outcomes among living kidney donors. N Engl Med 2010;363:724-32.

24. Muzaale AD, Massie AB, Wang MCh, Montgomery RA, McBride MA, WainriqhtJL, et al.Risk of end-stage renal disease following live kidney donation. Jamafeb 2014;311(6):580.

25. GardAX, Nevis IF, Mcarthur E, Sontrop JM, KovalJJ, Lam NN. Et al. Gestational hypertension and preeclampsia in living kidney donors. N Engl Med 2014;14:1-10.
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