Palabras clave
Procalcitonina
Trasplante Renal
Cómo citar
Resumen
Contexto: la procalcitonina (PCT) podría ser útil en la evaluación de la función del injerto renal (IR) en el postrasplante inmediato, ya que sus niveles se incrementan posterior a la elevación de citocinas inflamatorias (IL-6, TNF-?) durante eventos de disfunción renal.
Objetivo: determinar la asociación de la PCT sérica con la función del injerto renal en el periodo postrasplante inmediato.
Metodología: cohorte retrospectiva de septiembre del 2018 a abril del 2019 en la División de Nefrología y Trasplantes, del Centro Médico Nacional de Occidente (CMNO), del Instituto Mexicano del Seguro Social (IMSS). Se incluyeron 62 receptores de trasplante renal de donante vivo (DV) y fallecido (DF) con determinación de PCT en los primeros 7 días del TR y el registro de eventos de disfunción temprana del injerto (DTI), fueron comparados con pacientes sin DTI (sDTI).
Resultados: los receptores con DTI presentaron niveles más altos de PCT (13,90, 3,90, 1,22 ng/mL) comparado con el grupo sin DTI (0,32, 0,31 y 0,22 ng/ml) en los días 1, 3 y 5 respectivamente; p < 0,05.
Conclusiones: la PCT es un marcador biológico asociado a DTI en el postrasplante renal inmediato.
Citas
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