Risk factors for technique failure in peritoneal dialysis: A retrospective cohort study
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Risk factors
End stage renal disease
Peritoneal dialysis
failure of technique
Cohort study

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Benavides Cruz J, Rubio Romero JA, Sanabria Arenas RM. Risk factors for technique failure in peritoneal dialysis: A retrospective cohort study. Rev. Colomb. Nefrol. [Internet]. 2022 Sep. 9 [cited 2024 Jul. 16];9(2). Available from: https://revistanefrologia.org/index.php/rcn/article/view/580


Background: The technique failure in peritoneal dialysis can occur in an unplanned way, affecting health costs and the patient's quality of life.

Purpose: The aims of this study were to estimate the incidence of technique failure and mortality; and to determine the risk factors associated with time to failure of technique due to medical causes in the first year of renal replacement therapy.

Methodology: Retrospective cohort study that included 2192 incident patients on peritoneal dialysis using the records of Baxter renal therapy centers in Colombia, during the period January 2016 and December 2017. The incidence rate and mortality rate were estimated. Multivariate Cox regression analysis was used to determine risk factors for technique failure.

Results: An incidence rate of failure of the technique of 8.8/100 person-years was estimated. The mortality rate was 7.9/100 person-years. The multivariate Cox regression model showed as risk factors arterial hypertension (HR: 1.59; 95% CI 1.01-2.48) and male sex (HR: 1.62; 95% CI 1.03-2.56); and the protective factors were Kt / V> 1.7 (HR: 0.41; CI95% 0.25-0.65) and increase 1 gr / dl of albumin (HR: 0.61; CI95% 0.43-0.87).

Conclusions: The incidence rate of technique failure in the first year of peritoneal dialysis in Colombia was low and mechanical dysfunction was the main cause. The risk factors associated with time to failure of the technique were arterial hypertension and male gender.

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