Risk factors for technique failure in peritoneal dialysis: A retrospective cohort study
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Keywords

Risk factors
End stage renal disease
Peritoneal dialysis
Incidence
failure of technique
Cohort study

How to Cite

1.
Benavides Cruz J, Rubio Romero JA, Sanabria Arenas RM. Risk factors for technique failure in peritoneal dialysis: A retrospective cohort study. Rev. Colomb. Nefrol. [Internet]. 2022 Sep. 9 [cited 2022 Sep. 24];9(2). Available from: https://revistanefrologia.org/index.php/rcn/article/view/580

Abstract

Background: The technique failure in peritoneal dialysis can occur in an unplanned way, affecting health costs and the patient's quality of life.

Purpose: The aims of this study were to estimate the incidence of technique failure and mortality; and to determine the risk factors associated with time to failure of technique due to medical causes in the first year of renal replacement therapy.

Methodology: Retrospective cohort study that included 2192 incident patients on peritoneal dialysis using the records of Baxter renal therapy centers in Colombia, during the period January 2016 and December 2017. The incidence rate and mortality rate were estimated. Multivariate Cox regression analysis was used to determine risk factors for technique failure.

Results: An incidence rate of failure of the technique of 8.8/100 person-years was estimated. The mortality rate was 7.9/100 person-years. The multivariate Cox regression model showed as risk factors arterial hypertension (HR: 1.59; 95% CI 1.01-2.48) and male sex (HR: 1.62; 95% CI 1.03-2.56); and the protective factors were Kt / V> 1.7 (HR: 0.41; CI95% 0.25-0.65) and increase 1 gr / dl of albumin (HR: 0.61; CI95% 0.43-0.87).

Conclusions: The incidence rate of technique failure in the first year of peritoneal dialysis in Colombia was low and mechanical dysfunction was the main cause. The risk factors associated with time to failure of the technique were arterial hypertension and male gender.

https://doi.org/10.22265/acnef.9.2.580
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References

Organización Panamericana de la Salud. Comunicado de prensa: OPS/OMS y la Sociedad Latinoamericana de Nefrología llaman a prevenir la enfermedad renal y a mejorar el acceso al tratamiento [Internet]. 2015 [citado 2021 en. 23]. Disponible en: https://www.paho.org/hq/index.php?option=com_content&view=article&id=10542:2015-opsoms-sociedad-latinoamericana-nefrologia-enfermedad-renal-mejorar-tratamiento&Itemid=1926&lang=es.

Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A, et al. GBD 2015 Mortality and Causes of Death Collaborators. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016 oct. 8;388(10053):1459-544. http://dx.doi.org/10.1016/S0140-6736(16)31012-1

United States Renal Data System. 2020 USRDS Annual Data Report: Epidemiology of kidney disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD [Internet]. 2020 [citado 2021 febr. 20]. Disponible en: https://adr.usrds.org/2020/

Cuenta de Alto Costo (CAC). Situación la enfermedad renal crónica, la hipertensión arterial y la diabetes mellitus en Colombia 2019. Cuenta de Alto Costo: Bogotá D. C.; 2020.

Luyckx VA, Tonellib M, Staniferc JW. The global burden of kidney disease and the sustainable development goals. Bull World Health Organ. 2018;96:414-422C. http://dx.doi.org/10.2471/BLT.17.206441

Rosselli D, DeAntonio R, Calderón C. Análisis económico de diálisis peritoneal comparada con hemodiálisis en pacientes con enfermedad renal crónica, diabética o hipertensiva. MedUNAB. 2008;11(3):201-5.

Kunal C. Peritoneal Dialysis Drop-out: Causes and Prevention Strategies. Int J Nephrol. 2011;434608. https://doi.org/10.4061/2011/434608

Lan PG, Clayton PA, Johnson DW, McDonald SP, Borlace M, Badve SV, et al. Duration of Hemodialysis Following Peritoneal Dialysis Cessation in Australia and New Zealand: Proposal for a Standardized Definition of Technique Failure. J Int Soc Perit Dial. 2016;36(6):623-30. https://doi.org/10.3747/pdi.2015.00218

Jaar BG, Plantinga LC, Crews DC, Fink NE, Hebah N, Coresh J, et al. Timing, causes, predictors and prognosis of switching from peritoneal dialysis to hemodialysis: a prospective study. BMC Nephrol. 2009;10(3). https://doi.org/10.1186/1471-2369-10-3

See EJ, Johnson DW, Hawley CM, Pascoe EM, Badve SV, Boudville N, et al. Risk predictors and causes of technique failure within the first year of peritoneal dialysis: an Australia and New Zealand dialysis and transplant registry (ANZDATA) Study. Am J Kidney Dis. 2018 ag.;72(2):188-97. https://doi.org/10.1053/j.ajkd.2017.10.019

Chidambaram M, Bargman JM, Quinn RR, Austin PC, Hux JE, Laupacis A. Patient and physician predictors of peritoneal dialysis technique failure: a population based, retrospective cohort study. Perit Dial Int. 2011;31(5):565-73. https://doi.org/10.3747/pdi.2010.00096

Kolesnyk I, Dekker FW, Boeschoten EW, Krediet RT. Time-dependent reasons for peritoneal dialysis technique failure and mortality. Perit Dial Int. 2010;30(2):170-7. https://doi.org/10.3747/pdi.2008.00277

Guo A, Mujais S. Patient and technique survival on peritoneal dialysis in the United States: evaluation in large incident cohorts. Kidney Int Suppl. 2003 dic.;(88):S3-12. https://doi.org/10.1046/j.1523-1755.2003.08801.x

Hayat A, Saweirs W. Predictors of technique failure and mortality on peritoneal dialysis: An analysis of New Zealand peritoneal dialysis registry data. Nephrology (Carlton). 2020 nov. 22. https://doi.org/10.1111/nep.13837

Chan S, Cho Y, Koh YH, Boudville NC, Clayton PA, McDonald SP, et al. Association of Socio-Economic Position with Technique Failure and Mortality in Australian Non-Indigenous Peritoneal Dialysis Patients. Perit Dial Int. 2017;37(4):397-406. https://doi.org/10.3747/pdi.2016.00209

McGill RL, Weiner DE, Ruthazer R, Miskulin DC, Meyer KB, Lacson E. Transferencias a hemodiálisis entre pacientes estadounidenses que inician la terapia de reemplazo renal con diálisis peritoneal. Am J Kidney Dis. 2019;74(5):620-8. https://doi.org/10.1053/j.ajkd.2019.05.014

Shen JI, Mitani AA, Saxena AB, Goldstein BA, Winkelmayer WC. Determinants of peritoneal dialysis technique failure in incident US patients. Perit Dial Int. 2013;33(2):155-66. https://doi.org/10.3747/pdi.2011.00233

Nadeau-Fredette AC, Hawley C, Pascoe E, Chan CT, Leblanc M, Clayton PA, et al. Predictors of transfer to home hemodialysis after peritoneal dialysis completion. Perit Dial Int. 2016;36(5):547-54. https://doi.org/10.3747/pdi.2015.00121

Giuseppe E, Mallamaci F, Benedetto F, Panuccio V, Parlongo S, Cutrupi S, et al. Long?term CAPD patients are volume expanded and display more severe left ventricular hypertrophy than haemodialysis patients. Nephrol Dial Trans. 2001;16(7):1459-64. https://doi.org/10.1093/ndt/16.7.1459

Ortega LM, Materson BJ. Hypertension in peritoneal dialysis patients: epidemiology, pathogenesis, and treatment. J Am Soc Hypertens. 2011;5(3):128-36. https://doi.org/10.1016/j.jash.2011.02.004

Unal A, Hayri-Sipahioglu M, Kocyigit I, Elmali F, Tokgoz B, Oymak O. Does body mass index affect survival and technique failure in patients undergoing peritoneal dialysis? Pak J Med Sci. 2014 en.;30(1):41-4. https://doi.org/10.12669/pjms.301.3807

Lo WK, Ho YW, Li CS, Wong KS, Chan TM, Yu AW, et al. Effect of Kt/V on survival and clinical outcome in CAPD patients in a randomized prospective study. Kidney Int. 2003;64(2):649-56. https://doi.org/10.1046/j.1523-1755.2003.00098.x

Paniagua R, Amato D, Vonesh E, Correa-Rotter R, Ramos A, Moran J, et al. Effects of increased peritoneal clearances on mortality rates in peritoneal dialysis: ADEMEX, a prospective, randomized, controlled trial. J Am Soc Nephrol. 2002;13:1307-20. https://doi.org/10.1681/ASN.V1351307

Ahmad S. Manual of Clinical Dialysis. Washington, USA: Springer; 2009.

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