Patients undergoing solid organ transplants are at risk of developing malignant and infectious diseases related to the magnitude and timing of immunosuppressive therapy, Cutaneous infections are one of the most frequent complications in these patients, viral warts being the most common clinical manifestation caused by the human papilloma virus, a DNA virus belonging to the family of the Papillomaviridae, with at least 100 serotypes, some of these with high oncogenic potential, and with a high risk of developing anogenital tract or cervical malignancies. These lesions are rarely present before the first year after transplantation and its frequency increases in direct proportion to the age of transplantation, affecting about 80% of patients after the fifth year post-transplant. In general, they are successfully treated with conventional treatments such as cryotherapy, curettage and some compounds as topical retinoids, imiquimod and cases of successful treatment with cidofovir have recently been reported. In this paper, a case which was refractory to conventional treatment is described, and new management strategies are proposed.
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