Abstract
Mycosis by exophiala xenobiotica comprise a broad clinical spectrum in immunosuppressed patients, from localized to disseminated infections. They are a recognized etiology of phaeohyphomycosis, currently considered as emerging fungal infections in transplanted solid organ recipients. We present 2 cases of mycosis by exophiala xenobiotica in kidney transplant recipients, a localized cutaneous mycosis and a systemic infection with central nervous system involvement.
References
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7. Orozco R. Interacciones farmacológicas en trasplante. Revista Médica Clínica Las Condes. 2010;21(2):248-253. https://doi.org/
10.1016/S0716-8640(10)70531-9
2. Palmisano A, Morio F, Le Pape P, Degli A, Ricci R, Zucchi A, et al. Multifocal phaeohyphomycosis caused by exophiala xenobiotica in a kidney transplant recipient. Transpl Infect Dis. 2015;17(2):297-302. https://doi.org/10.1111/tid.12350
3. Revankar S, Patterson J, Sutton D, Pullen R, Rinaldi M. Disseminated phaeohyphomycosis: review of an emerging mycosis. Clin Infect Dis. 2002; 15(34):467-76. https://doi.org/10.1086/338636
4. Chowdhary A, Meis J, Guarro J, De Hoog G, Kathuria S, Arendrup M., et al. ESCMID and ECMM joint clinical guidelines for the diagnosis and management of systemic phaeohyphomycosis: diseases caused by black fungi. Clin Microbiol Infect 2014;20(Suppl 3):47-75. https://doi.org/10.1111/1469-0691.12515
5. Schieffelin J, Garcia-Diaz J, Loss G Jr, Beckman E, Keller R, Staffeld-Coit Ce, et al. Phaeohyphomycosis fungal infections in solid organ transplant recipients: clinical presentation, pathology, and treatment. Transpl Infect Dis. 2014;16 (2): 270-78. https://doi.org/10.1111/tid.12197
6. Ogawa M, Galante N, Godoy P, Fischman-Gompertz O, Martelli F, Colombo A, et al. Treatment of subcutaneous phaeohyphomycosis and prospective follow-up of 17 kidney transplant recipients. J Am Acad Dermatol. 2009;61(6):977-985. https://doi.org/10.1016/ j.jaad.2009.03.037
7. Orozco R. Interacciones farmacológicas en trasplante. Revista Médica Clínica Las Condes. 2010;21(2):248-253. https://doi.org/
10.1016/S0716-8640(10)70531-9
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