@article{Córdoba_Contreras_Hurtado_Pinto_Rodriguez_Larrarte_2014, title={Therapeutic plasma exchange in patients with pauciimmune vasculitis: Hospital Universitario San Ignacio experience; Bogotá, Colombia}, volume={1}, url={https://revistanefrologia.org/index.php/rcn/article/view/167}, DOI={10.22265/acnef.1.1.167}, abstractNote={<p><strong>Introduction:</strong> The vasculitis ANCAS positive, are a group of diseases with different clinical manifestations. Therapeutic plasma exchange has become an excellent tool for the treatment of these patients in specific conditions.</p> <p><strong>Objective</strong>: Describe the demographic and clinical characteristics of patients and the final outcomes in patients with positive ANCAS vasculitis that required therapeutic plasma exchange (TPE).</p> <p><strong>Materials and methods:</strong> All patients under 18 years old with positive ANCAS vascultiis that required TPE where included during the period of May 2010 and December 2013.</p> <p><strong>Results:</strong> 13 patients where treated, with a total of 73 TPE sessions. The average age was 52,3 years (Range 17 to 70). The principal diagnosis for interventions was rapidly progressive glomerulonephritis (RPGN) plus alveolar hemorrhage (63%). The average number of sessions per patient was 5,6 (range 1 a 10) with an average of plasma volume exchange per session of 1,26 (range 0.72 a 1,56). Of the 13 patients, 11 (84,6%) required renal replacement therapy (RRT) during hospitalization. At discharge, 36.3% recover the renal function, 27% continue on RRT and 36,3% died. There was at least one complication in 6,8% of all sessions.</p> <p><strong>Conclusions:</strong> TPE is an excellent tool to treat patients with positive ANCAS vasculitis that present with RPGN, high levels of serum creatinine or dialysis need, or alveolar hemorrhage. This is a safe procedure with comparable results according to International literature.</p>}, number={1}, journal={Revista Colombiana de Nefrología}, author={Córdoba, Juan P. and Contreras, Kateir and Hurtado, Maite and Pinto, Jessica and Rodriguez, Martha P. and Larrarte, Carolina}, year={2014}, month={Jan.}, pages={3–9} }